Presentation

The subplate is an early generated, transient and heterogeneous population of neurons that has fundamental roles in the establishment of cortical circuitries and is implicated in various neurological disorders. Despite their importance, very little is known today about the mechanisms that control their specification. Our aim here is to understand how the zinc finger transcription factor Dmrt5 that has been shown recently by one of the partners of the project to be required for cortical SP neurons controls their generation.

Promoters

  • Eric Bellefroid, Institute of Molecular Biology and Medicine (IBMM), ULB
  • Zoltán Molnar, Department of Physiology, Anatomy and Genetics, University of Oxford